Helicobactor pylori infection and gastric carcinoma in Babylon governorate

Abstract EN

The study aimed to determine the relationship between I-I.

pylori & gastric ca.The period of the study covered 24 months and started in Nov.

1997.

37 patients with gastric ca.

entered into the study and the diagnosis of gastric carcinoma was made by clinical examination and confirmed by upper GIT endoscopy and histopathological examination.

Also eighty four subjects were taken as healthy control.

Three antral biopsy specimens were taken , inaddition to biopsy from the lesion, and these specimens were subjected to the three main important methods, including : Urease test Microbiological culture Histopathological changes in the gastric mucosa .

The results show that 30 out of 37 patients ( 8 1.1 % ) has got evidence of H.

pylori infection associated with sever atrophy of gastric glands, intestinal metaplasia and marked inflammatory cells & polymophs infiltrations in the intraepithelial regions and lamina properia .

The control group shows only 19 % positive evidence of H.

pylori infection .