C-reactive protein and plasma fibrinogen in patients with stable angina pectoris

Abstract EN

The study included 48 patients with stable angina pectoris and 41 control subjects to evaluate the association between inflammatory markers (C-reactive protein and plasma fibrinogen) and angina pectoris.

The study revealed that plasma fibrinogen (P<0.001), C-reactive protein (P<0.01), as well as lipid profile (total cholesterol (P<0.001), low-density lipoprotein cholesterol (P<0.01), triglycerides (P<0.01) and low-density lipoprotein cholesterol/high-density lipoprotein cholesterol ratio (P<0.01) were significantly higher among patients with stable angina pectoris compared to controls.

While, there was no significant differences in high-density, lipoprotein cholesterol level between patients and controls (P>0.05).

The present study clearly demonstrated a strong association between inflammatory markers and angina pectoris, suggesting a role for these markers in the pathogenesis and the progression of coronary heart disease.