Testing bromocriptine dose necessary for suppression of lactation in rats : morphological study

Abstract EN

Objectives : The lowest dose of bromocriptine, necessary for suppression of lactation in rats, was estimated in this investigation.

Methodology : Fifty healthy lactating rats were treated with different doses of bromocriptine.

Cessation of lactation was assessed clinically and histologically.

Results : Revealed that the lowest dose capable of lactation suppression is 4 mg bromocriptine / kg body wt.

/ day.

It is very important to know the exact dose, which can suppress lactation in rats because these laboratory animals are commonly employed in experiments concerning this topic.