A comparative study between the effects of two different antihypertensive drugs on the salivary flow rate and salivary compositions

Abstract EN

This study investigated the possible abnormalities and variations in salivary flow rate and compositions in two groups of patients under the effects of two different types of antihypertensive drugs (Atenolol and Captopril) one on hand compared with third group of normotensives (As control) on the other hand.

Results : It was obvious that there is marked reduction in the salivary flow rate in those taken the antihypertensive drugs in comparison with control group of normotensives.

Significantly elevated levels of potassium, phosphorus, and proteins had been realized as first result of this study which might be explained due to the continuous adrenergic over stimulation of salivary gland in hypertensives under taking Atenolol, magnesium in saliva appear reduced in treated hypertensives with Captopril than with Atenolol.

Whereas there is dropping in the level of sodium in the two groups than in the control.