Comparison of slope-intercept with single plasma sample methods in estimating glomerular filtration rate using radionuclides
Joint Authors
al-Madani, Ahmad al-Khidr
Uthman, Abd al-Baqi Umar
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 25, Issue 2 (30 Apr. 2014), pp.321-325, 5 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2014-04-30
Country of Publication
Saudi Arabia
No. of Pages
5
Main Subjects
Topics
Abstract EN
To evaluate the accuracy of different single plasma sample methods (SPSM) 99mTc- DTPA clearances and to test whether the SPSM can replace the dual plasma samples method (DPSM) in the measurement of glomerular filtration rate (GFR), we studied 430 subjects counting renal patients and donors (240 male, 190 female; mean age 43.40 ± 16.30 years).
All the subjects underwent dynamic renal scintigraphy after injection of 99mTc-DTPA ; the GFR was calculated by seven SPSMs in addition to DPSM as a reference.
Each of the SPSM clearance was compared with the DPSM measurement.
There was a high correlation of all the SPSMs and the DPSM.
The limits of agreement (95 %) were found between the DPSM and all the SPSMs.
Overall, the best method among the SPSMs, which is closest to the DPSM, is Fleming’s single method as it has a statistically significant low mean difference (bias), low standard error, close mean ± SD to the reference method, good limits of agreement and high correlation co-efficient.
This study concludes that, among the SPSMs, Fleming can reflect GFR more accurately than other methods, particularly when the expected serum creatinine is normal.
American Psychological Association (APA)
Uthman, Abd al-Baqi Umar& al-Madani, Ahmad al-Khidr. 2014. Comparison of slope-intercept with single plasma sample methods in estimating glomerular filtration rate using radionuclides. Saudi Journal of Kidney Diseases and Transplantation،Vol. 25, no. 2, pp.321-325.
https://search.emarefa.net/detail/BIM-363111
Modern Language Association (MLA)
Uthman, Abd al-Baqi Umar& al-Madani, Ahmad al-Khidr. Comparison of slope-intercept with single plasma sample methods in estimating glomerular filtration rate using radionuclides. Saudi Journal of Kidney Diseases and Transplantation Vol. 25, no. 2 (Apr. 2014), pp.321-325.
https://search.emarefa.net/detail/BIM-363111
American Medical Association (AMA)
Uthman, Abd al-Baqi Umar& al-Madani, Ahmad al-Khidr. Comparison of slope-intercept with single plasma sample methods in estimating glomerular filtration rate using radionuclides. Saudi Journal of Kidney Diseases and Transplantation. 2014. Vol. 25, no. 2, pp.321-325.
https://search.emarefa.net/detail/BIM-363111
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 325
Record ID
BIM-363111