Single vs. double embryos transfer and its impact on pregnancy rate

Abstract EN

Background : To decide the optimal number of embryos transferred in women undergoing tresh embryo transfer cycles, there are guidelines regarding the number of embryos to be fransferred during a fresh IVF cycle, which are used to reduce multiple pregnancy rates.

Because of the reported lower success rates in single embryo transfer, more embryos are often transferred in fresh cycles.

This practice, however, resulted in a significant increase in multiple pregnancy rates which are associated with maternal and perenatal morbidity and mortality. ©bjective : This study was designed to compare the both ICSI and pregnancy outcomes of single versus double embryos transfer. Method : This is a retrospective, observational study composed of 2 groups, Group 1: single embryo transfer (35) and Group 2: double embryos transfer (176), were enrolled in this study from October 2007 to October 2009, in C-PLAS Hospital Sana'a, Yemen. RESULTS : The ongoing Clinical Pregnancy Rate after Single Embryo Transfer was not significantly lower as compared with double Embryos Transfer (31.42 versus 42.22 %).

Delivery(live birth) rate was significantly lower in the Single Embryos Transfer group (25.71 % )versus (39.2% ) in the double Embryo Transfer group respectively, p =0.003), Multiple pregnancies were significantly higher in the double Embryos Transfer group when compared with the Single Embryo Transfer group (6.25% versus 0 % ) respectively, (PcO.OOl) Conclusion : Single embryo transfer results denoting satisfactory delivery rates and ،٦ dramatic decrease in the Multiple Birth Rates.

Delivery (live bil'th) rate was significantly lower in the Single Embryos Transfer than Double embryos