Age at diagnosis in women with non-metastatic breast cancer : is it related to prognosis?
Joint Authors
Ibrahim, Amal Sami
Salim, Salim Id
Ali al-Din, Nilli Hasan
Abu al-Azm, Umniyah M.
Bilal, Daliyah
Jawdah, Iman
al-Munji, Majidah
Source
Journal of the Egyptian National Cancer Institute
Issue
Vol. 26, Issue 1 (31 Mar. 2014), pp.23-30, 8 p.
Publisher
Cairo University National Cancer Institute
Publication Date
2014-03-31
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Topics
Abstract EN
Primary objective was to verify whether breast cancer patients aged less than 40 years at diagnosis have poorer prognosis than older patients.
Secondary to assess prognostic factors influencing disease free survival.
Methods : 941 women were diagnosed with non-metastatic breast cancer at NCI, Cairo in 2003.
Epidemiologic, clinico-pathological characteristics, treatment modalities and disease free survival were compared among the two age groups.
Prognostic factors were evaluated for association with disease-free survival.
Results : One hundred-eighty-one patients (19.2 %) were younger than 40 years and 760 (80.8 %) were older.
Older women presented with higher rates of comorbidities and younger women presented with more hormone non-responsive tumors.
Young women presented with larger tumors pT4 = 13.8 % compared to 8.6 % in older women, yet not significant.
Young women were treated with more conservative surgery, more adjuvant chemotherapy and radiotherapy while older women with more radical mastectomies and more hormonal treatment.
Recurrence rates were significantly higher among young women 44.2 % compared to 34.5 % in older women.
Five year disease free.
American Psychological Association (APA)
Ali al-Din, Nilli Hasan& Abu al-Azm, Umniyah M.& Bilal, Daliyah& Salim, Salim Id& Jawdah, Iman& al-Munji, Majidah…[et al.]. 2014. Age at diagnosis in women with non-metastatic breast cancer : is it related to prognosis?. Journal of the Egyptian National Cancer Institute،Vol. 26, no. 1, pp.23-30.
https://search.emarefa.net/detail/BIM-365224
Modern Language Association (MLA)
Ali al-Din, Nilli Hasan…[et al.]. Age at diagnosis in women with non-metastatic breast cancer : is it related to prognosis?. Journal of the Egyptian National Cancer Institute Vol. 26, no. 1 (2014), pp.23-30.
https://search.emarefa.net/detail/BIM-365224
American Medical Association (AMA)
Ali al-Din, Nilli Hasan& Abu al-Azm, Umniyah M.& Bilal, Daliyah& Salim, Salim Id& Jawdah, Iman& al-Munji, Majidah…[et al.]. Age at diagnosis in women with non-metastatic breast cancer : is it related to prognosis?. Journal of the Egyptian National Cancer Institute. 2014. Vol. 26, no. 1, pp.23-30.
https://search.emarefa.net/detail/BIM-365224
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 29-30
Record ID
BIM-365224