Seizure as a presenting manifestation of idiopathic hypoparathyroidism

Abstract EN

A 31-year-old male presented with generalized new-onset tonic-clonic seizure related to severe hy-pocalcaemia (serum calcium 1.2 mmol / l) caused by idiopathic hypoparathyroidism (parathyroid hormone concentration 6pg ; normal 1 5-65pg).

Computerized tomographic scan showed bilateral, symmetrical, intracranial calcifications involving the basal ganglia and the cerebellum.

There are few reports in clinical literature describing new-onset seizure caused by primary hypoparathyroidism in adulthood and hypoparathyroidism needs to be considered in the differential diagnosis of adult-onset seizure.