Impact of obesity on development of chronic renal allograft dysfunction
Joint Authors
Roozbeh, Jamshid
Jalali, Ghanbar Ali Raiss
Jahromi, Ali Reza Hamidiyan
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 20, Issue 3 (30 Jun. 2009), pp.375-377, 3 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2009-06-30
Country of Publication
Saudi Arabia
No. of Pages
3
Main Subjects
Topics
Abstract EN
Obesity in nontransplant patients has been associated with hypertension, hyperlipidemia, diabetes, and proteinuria.
To determine whether renal transplant recipients with an elevated BMI have worse long term graft survival, we prospectively studied 92 patients transplanted between April 1999 and July 2000.
Weight (Wt) and height of the patients were recorded prior to transplantation and two weeks, one, two and three years post transplantation.
Blood urea nitrogen (BUN), creatinine (Cr) and blood pressure were checked monthly, while triglyceride, cholesterol, high density lipoprotein (HDL), and low density lipoprotein (LDL) were obtained 3 monthly for 3 years post transplantation.
Graft dysfunction was defined as serum Cr > 1.8 mg / dL.
While BMI and Wt of the patients before transplantation did not show any significant correlation with chronic renal allograft dysfunction (CRAD), patients with higher Wt and BMI two weeks after transplantation showed an increased risk of developing CRAD during the three year post transplant independent of other risk factors (P< 0.05).
Patients with greater Wt loss in the first two weeks post transplantation showed a decreased risk of developing CRAD in the following 3 years (P< 0.001).
Our study suggests that high Wt and BMI are significantly associated with worse graft survival 3 years post renal transplantation.
American Psychological Association (APA)
Jahromi, Ali Reza Hamidiyan& Jalali, Ghanbar Ali Raiss& Roozbeh, Jamshid. 2009. Impact of obesity on development of chronic renal allograft dysfunction. Saudi Journal of Kidney Diseases and Transplantation،Vol. 20, no. 3, pp.375-377.
https://search.emarefa.net/detail/BIM-36645
Modern Language Association (MLA)
Jahromi, Ali Reza Hamidiyan…[et al.]. Impact of obesity on development of chronic renal allograft dysfunction. Saudi Journal of Kidney Diseases and Transplantation Vol. 20, no. 3 (Sep. 2009), pp.375-377.
https://search.emarefa.net/detail/BIM-36645
American Medical Association (AMA)
Jahromi, Ali Reza Hamidiyan& Jalali, Ghanbar Ali Raiss& Roozbeh, Jamshid. Impact of obesity on development of chronic renal allograft dysfunction. Saudi Journal of Kidney Diseases and Transplantation. 2009. Vol. 20, no. 3, pp.375-377.
https://search.emarefa.net/detail/BIM-36645
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 377
Record ID
BIM-36645