Effect of the type of input on the periodic operation of a bioreactor with input multiplicities

Abstract EN

The effect of periodic inlet substrate concentration cycling in different input forms on the time average productivity of continuous fermentation process is theoretically studied.

Four types of input forms were used: Pseudo Random Binary Sequence (PRBS), rectified sinusoidal, sinusoidal, and saw teeth signals.

The obtained time average productivity with inlet substrate concentration (Sf) cycling in the different forms was compared with that of the steady state operation for the purpose of productivity improvement.

The effect of periodic operation with dilution rate (D) cycling in different forms on the time average productivity was also studied.

It was found that the periodic operation with Sf cycling improved the performance of the process especially at the optimum productivity.

Cycling of the dilution rate D was found to have an inferior effect on the productivity.