Synthesis and characterization of new fused heterocyclic compounds consisting of benzodiazepine, quinoxaline, benzimidazole and thiazole rings
Other Title(s)
تحضير و تشخيص مركبات حلقية غير متجانسة ملتحمة جديدة تحتوي على حلقات البنزوددايأيزوأبين، الكوينوكزالين، البنزايمدازول و الثايزول
Joint Authors
Salih, Nadiyah Adil
Ibrahim, Hanan Abd al-Latif
Source
Issue
Vol. 5, Issue 3 (30 Sep. 2008)6 p.
Publisher
University of Baghdad College of Science for Women
Publication Date
2008-09-30
Country of Publication
Iraq
No. of Pages
6
Main Subjects
Abstract EN
In this study, new heterocyclic compounds were synthesized through the cyclization reactions of o-phenylenediamine (1) with various organic reagents.
Benzodiazepine derivatives (2-4) were obtained by reaction of (1) with ethylacetoacetate, malonic acid and acetyl acetone.Treatment of compound (1) with chloroacetamide, chloroacetic acid, p-bromophenacyl bromide and oxalic acid dihydrate afforded quinoxaline derivatives (5-8), respectively.
Reaction of compound (1) with benzoic acid, piperonal, cyclohexanone and carbon disulfide resulted in the formation of compounds (9-12), respectively.
Finally, reaction of compound (12) with chloroacetic acid in the presence of potassium hydroxide produced compound (13).
American Psychological Association (APA)
Salih, Nadiyah Adil& Ibrahim, Hanan Abd al-Latif. 2008. Synthesis and characterization of new fused heterocyclic compounds consisting of benzodiazepine, quinoxaline, benzimidazole and thiazole rings. Um-Salama Science Journal،Vol. 5, no. 3.
https://search.emarefa.net/detail/BIM-367277
Modern Language Association (MLA)
Salih, Nadiyah Adil& Ibrahim, Hanan Abd al-Latif. Synthesis and characterization of new fused heterocyclic compounds consisting of benzodiazepine, quinoxaline, benzimidazole and thiazole rings. Um-Salama Science Journal Vol. 5, no. 3 (2008).
https://search.emarefa.net/detail/BIM-367277
American Medical Association (AMA)
Salih, Nadiyah Adil& Ibrahim, Hanan Abd al-Latif. Synthesis and characterization of new fused heterocyclic compounds consisting of benzodiazepine, quinoxaline, benzimidazole and thiazole rings. Um-Salama Science Journal. 2008. Vol. 5, no. 3.
https://search.emarefa.net/detail/BIM-367277
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-367277