Methicillin-resistant Staphylococcus aureus causing post operative infections
Dissertant
Thesis advisor
Umar, Muhammad al-Fatih Ahmad
Mustafa, Asim Faruq
University
Omdurman Islamic University
Faculty
Faculty of Pharmacy
Department
Department of Pharmaceutical Microbiology
University Country
Sudan
Degree
Master
Degree Date
2012
English Abstract
This study was designed to determine the prevalence of MRSA isolates among Staphy lococcusaureus isolated and 103 samples screened from GIT& URO surgical ward.
The isolated Methicilllin-resistant Staphylococcusaureus (MRSA), exhibited high resistance to tested antibiotics (including Penicillin (G) ,Ofloxacillin, Amikacin and Vancomycin.). Clinical samples (290) were obtained from patients developed post-operative infection in ibn Sina Hospital Khartoum and Omdurman teaching hospital, from which 33 Staphylococcusaureusspecies were identified from 200 samples (ibn Sina Hospital Khartoum), and 70 Staphylococcusaureusspecies from90 samples (Omdurman Teaching Hospital).
The samples were cultivated on Mannitol Salt Agar, which is a selective and differential media for the isolation of Staphylococcusaureus. Growth was recovered only in 103 plates.
The microorganisms were then identified by examining the morphological features using the Gram-stain and confirmed by 2 biochemical tests : Coagulase and DNase. The 103 clinical isolates of Staphylococcusaureus were then tested for their susceptibility to 6 antibiotics: Amikacin, Methicillin, Ofloxacin,Oxacillin,Pencillin G and Vancomycin. The results indicated that 35.5 % of post-operative infections in Ibn Sina Hospital and Omdurman Teaching Hospital were due to Staphylococcus aureus. The obtained results indicated alarming high levels of drug resistance in the tested clinical isolates.
Almost all of the isolates were resistant to penicillin G, 75 % of them were Methicillin resistant.
Only (8 %) were Vancomycin resistant, Also show 59% were resistant to Ofloxacin and 25% of the isolate were resistant to Amikacin and 70 % resistant to Oxacillin.
Main Subjects
Topics
No. of Pages
107
Table of Contents
Table of contents.
Abstract.
Chapter One : Introduction and literature review.
Chapter Two : Materials and methods.
Chapter Three : Results.
Chapter Four : Discussion.
Conclusion and recommendation.
References.
American Psychological Association (APA)
Ali, Najla Awwad al-Karim. (2012). Methicillin-resistant Staphylococcus aureus causing post operative infections. (Master's theses Theses and Dissertations Master). Omdurman Islamic University, Sudan
https://search.emarefa.net/detail/BIM-367592
Modern Language Association (MLA)
Ali, Najla Awwad al-Karim. Methicillin-resistant Staphylococcus aureus causing post operative infections. (Master's theses Theses and Dissertations Master). Omdurman Islamic University. (2012).
https://search.emarefa.net/detail/BIM-367592
American Medical Association (AMA)
Ali, Najla Awwad al-Karim. (2012). Methicillin-resistant Staphylococcus aureus causing post operative infections. (Master's theses Theses and Dissertations Master). Omdurman Islamic University, Sudan
https://search.emarefa.net/detail/BIM-367592
Language
English
Data Type
Arab Theses
Record ID
BIM-367592
