Biological and phytochemical evaluation of two Sudanese plants of claimed hypoglycemic effect
Dissertant
Thesis advisor
Hasan, Abd al-Wahhab
Middawi, Mahmud
University
Omdurman Islamic University
Faculty
Faculty of Pharmacy
University Country
Sudan
Degree
Master
Degree Date
2011
English Abstract
The effects of ethanol extracts of Schouwia schimperi and Argemone Mexicana were investigated experimentally in glucose-loaded-rats, and streptozotocin induced-diabetic rats for their hypoglycemic activity and their impact on cholesterol and triglyceride levels. The ethanol extracts of the both plants were given at the doses of 200mg / kg and 400mg / kg body weight to glucose loaded wistar albino rats (2g / kg), and streptozotocin-induced- diabetic rats.
They caused significant reduction in plasma glucose levels (P < 0.05) at doses of 400 and 200 mg / kg Bwt.
in glucose loaded The effects Schouwia schimperi ethanol extract at the dose of 200 mg / kg were more prominent than those of glibenclamide which was taken as arefference standard.
Both extracts showed a significant reduction in cholesterol level (P < 0.05, p < .001), and Schouwia schimperi at the dose of 200 mg / kg reduced the triglycerides level significantly( p < .001). Also some phytochemical screening tests were made for these extracts and the results revealed that Argemone Mexicana contains high amounts of alkaloids, moderate quantities of deoxy-sugars and trace amounts of terpenoides, flavonoides and, tannins.
While schouwia schimperi contains high quantities of terpenoides, tannins and saponins besides moderate quantities of flavonoides and deoxy-sugars and trace amounts of alkaloids.
Main Subjects
Topics
No. of Pages
60
Table of Contents
Table of contents.
Abstract.
Introduction.
Chapter One : Literature review.
Chapter Two : Materials and methods.
Chapter Three : Results.
Chapter Four : Discussion.
Conclusion and recommendations.
References.
American Psychological Association (APA)
Muhammad, Ahmad Ibrahim. (2011). Biological and phytochemical evaluation of two Sudanese plants of claimed hypoglycemic effect. (Master's theses Theses and Dissertations Master). Omdurman Islamic University, Sudan
https://search.emarefa.net/detail/BIM-367814
Modern Language Association (MLA)
Muhammad, Ahmad Ibrahim. Biological and phytochemical evaluation of two Sudanese plants of claimed hypoglycemic effect. (Master's theses Theses and Dissertations Master). Omdurman Islamic University. (2011).
https://search.emarefa.net/detail/BIM-367814
American Medical Association (AMA)
Muhammad, Ahmad Ibrahim. (2011). Biological and phytochemical evaluation of two Sudanese plants of claimed hypoglycemic effect. (Master's theses Theses and Dissertations Master). Omdurman Islamic University, Sudan
https://search.emarefa.net/detail/BIM-367814
Language
English
Data Type
Arab Theses
Record ID
BIM-367814