Spectrophotometric determination of procaine penicillin in pure and pharmaceutical formulations using metol
Other Title(s)
القدير الطيفي للبروكائين بنيسيلين في الأشكال الصيدلانية و النقية باستخدام الميتول
Author
Source
Issue
Vol. 5, Issue 1 (31 Mar. 2008), pp.137-142, 6 p.
Publisher
University of Baghdad College of Science for Women
Publication Date
2008-03-31
Country of Publication
Iraq
No. of Pages
6
Main Subjects
Abstract EN
A simple, accurate and sensitive spectrophotometric method for the determination of Procaine penicillin (PP) is described.
The method is based on charge-transfer reaction of PP with metol (N-methyl-p-hydroxy aniline) in the presence of ferric sulphate to form a purple-water soluble complex ,which is stable and has a maximum absorption at 510 nm .A graph of absorbance versus concentration shows that Beer’s low is obeyed over the concentration range of 3-80 μg /ml of PP (i.e.,3-80 ppm) with a molar absorbativity of 4.945 ×103 L.mol-1.cm-1 ,Sandell sensitivity of 0.1190 μg cm-2 ,a relative error of (-1.57)-2.79 % and a standard deviation of less than 0.59 depending on the concentration of PP.The optimum conditions for full colour development are described and the proposed method was probably applied satisfactorily to pharmaceutical injections containing PP.
American Psychological Association (APA)
Abd Allah, Hind Hadi. 2008. Spectrophotometric determination of procaine penicillin in pure and pharmaceutical formulations using metol. Um-Salama Science Journal،Vol. 5, no. 1, pp.137-142.
https://search.emarefa.net/detail/BIM-367977
Modern Language Association (MLA)
Abd Allah, Hind Hadi. Spectrophotometric determination of procaine penicillin in pure and pharmaceutical formulations using metol. Um-Salama Science Journal Vol. 5, no. 1 (2008), pp.137-142.
https://search.emarefa.net/detail/BIM-367977
American Medical Association (AMA)
Abd Allah, Hind Hadi. Spectrophotometric determination of procaine penicillin in pure and pharmaceutical formulations using metol. Um-Salama Science Journal. 2008. Vol. 5, no. 1, pp.137-142.
https://search.emarefa.net/detail/BIM-367977
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 141
Record ID
BIM-367977