Spectrophotometric micro determination of pro-methazine hydrochloride in pharmaceutical dosage forms via oxidative coupling reaction with P-aminobenzoic acid and N-Bromosuccinimide
Other Title(s)
التقدير الطيفي لدواء البروميثازين هيدروككلوريد في المستحضرات الصيدلانية بواسطة تفاعل الازدواج التأكسدي مع P أمينو حامض البنزويك و N برومو سكسين أمايد
Joint Authors
Abd al-Rahman, Luayy Qasim
aI-Abbaji, Anas Muayyad
al-Qaysi, Myyadah H.
Source
Issue
Vol. 2, Issue 3 (30 Sep. 2005), pp.471-476, 6 p.
Publisher
University of Baghdad College of Science for Women
Publication Date
2005-09-30
Country of Publication
Iraq
No. of Pages
6
Main Subjects
Abstract EN
A simple, accurate and sensitive spectrophotometric method for the determination of promethazine.IIC1 has been developed.
The method is based on the oxidative coupling reaction of promethazine.
1 ICi with P-aminobenzoic acid and in the presence of N-bromosuceinimide to form an intense bluish-green water soluble dye that is stable and has a maximum absorption at 600nm.A graph of absorbance versus concentration shows that Beer’s law is obeyed over the concentration range of 50-750 j.ig of promethazine.I ICI in a final volume of 25ml.(i-e 2-30ppm) with a molar absorptivity of 1.0*10'* L modern'1, a recovery% of 98.10-101.00 and a relative standard deviation of better than 1.2% depending on the concentration .The optimum conditions for full colour development are described and the proposed method was applied satisfactorily to the pharmaceutical dosage forms
American Psychological Association (APA)
Abd al-Rahman, Luayy Qasim& aI-Abbaji, Anas Muayyad& al-Qaysi, Myyadah H.. 2005. Spectrophotometric micro determination of pro-methazine hydrochloride in pharmaceutical dosage forms via oxidative coupling reaction with P-aminobenzoic acid and N-Bromosuccinimide. Um-Salama Science Journal،Vol. 2, no. 3, pp.471-476.
https://search.emarefa.net/detail/BIM-368006
Modern Language Association (MLA)
Abd al-Rahman, Luayy Qasim…[et al.]. Spectrophotometric micro determination of pro-methazine hydrochloride in pharmaceutical dosage forms via oxidative coupling reaction with P-aminobenzoic acid and N-Bromosuccinimide. Um-Salama Science Journal Vol. 2, no. 3 (2005), pp.471-476.
https://search.emarefa.net/detail/BIM-368006
American Medical Association (AMA)
Abd al-Rahman, Luayy Qasim& aI-Abbaji, Anas Muayyad& al-Qaysi, Myyadah H.. Spectrophotometric micro determination of pro-methazine hydrochloride in pharmaceutical dosage forms via oxidative coupling reaction with P-aminobenzoic acid and N-Bromosuccinimide. Um-Salama Science Journal. 2005. Vol. 2, no. 3, pp.471-476.
https://search.emarefa.net/detail/BIM-368006
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 475-476
Record ID
BIM-368006