Colorectal involvement by post-transplant lymphoproliferative disorders : a review of 81 cases
Joint Authors
Amini, Muhsin
Qamar Chehreh, Muhammad Ibrahim
Khidmat, Husayn
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 25, Issue 3 (30 Jun. 2014), pp.597-604, 8 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2014-06-30
Country of Publication
Saudi Arabia
No. of Pages
8
Main Subjects
Topics
- Patients
- Colon
- Rectum
- Diseases
- Organ transplantation
- Prognosis
- Complications(Medicine)
- Tissue culture
- Lymphoproliferative disorders
- Diagnosis
Abstract EN
The reported number of patients representing post-transplant lymphoproliferative disorders (PTLD) within the colorectal region is quite limited.
In this study, we sought to analyze and compare the characteristics, predictors and prognosis of colorectal localization of PTLDs arising in transplant recipients.
A comprehensive search was performed through Pubmed and Google scholar to find case reports and series of colorectal localization of PTLD.
Data of each individual patient from different studies were entered into a database and analyzed.
Colorectal PTLD was significantly more prevalent in male patients (19.3 % vs.
8.5 %, respectively; P = 0.002) and represented a significantly shorter time to diagnosis than other localizations (P = 0.044).
Multiorgan involvement (75 % vs.
46 %, respectively ; P < 0.001) and disseminated disease (43 % vs.
26 %, respectively ; P = 0.014) were more frequently observed in the colorectal PTLD.
There was no survival difference between the two groups.
Organ recipients representing colorectal involvement by PTLD are significantly at higher risk for metastasis, especially in their small intestine.
Moreover, patients who underwent surgical intervention had low mortality, and, accordingly, we suggest using surgery to manage colorectal PTLD when it is applicable.
Prospective studies with larger patient populations are needed to confirm these results.
American Psychological Association (APA)
Khidmat, Husayn& Amini, Muhsin& Qamar Chehreh, Muhammad Ibrahim. 2014. Colorectal involvement by post-transplant lymphoproliferative disorders : a review of 81 cases. Saudi Journal of Kidney Diseases and Transplantation،Vol. 25, no. 3, pp.597-604.
https://search.emarefa.net/detail/BIM-370849
Modern Language Association (MLA)
Khidmat, Husayn…[et al.]. Colorectal involvement by post-transplant lymphoproliferative disorders : a review of 81 cases. Saudi Journal of Kidney Diseases and Transplantation Vol. 25, no. 3 (2014), pp.597-604.
https://search.emarefa.net/detail/BIM-370849
American Medical Association (AMA)
Khidmat, Husayn& Amini, Muhsin& Qamar Chehreh, Muhammad Ibrahim. Colorectal involvement by post-transplant lymphoproliferative disorders : a review of 81 cases. Saudi Journal of Kidney Diseases and Transplantation. 2014. Vol. 25, no. 3, pp.597-604.
https://search.emarefa.net/detail/BIM-370849
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 601-604
Record ID
BIM-370849