Serum trypsin inhibitory capacity in hemodialysis patients
Joint Authors
Hashimi, Muhammad
Mehrabifar, Hamid
Homayooni, Fatimah
Nadiri, Muhammad
Muntazarifar, Farzaneh
Ghavami, Said
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 20, Issue 4 (31 Aug. 2009), pp.604-607, 4 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2009-08-31
Country of Publication
Saudi Arabia
No. of Pages
4
Main Subjects
Topics
Abstract EN
It has been established that overproduction of reactive oxygen species (ROS) occurs during hemodialysis causing oxidation of proteins.
Alpha-1-antitrypsin is the major circulating antiprotease which contains methionine in the active site.
The aim of the present study was to measure the level of serum trypsin inhibitory capacity (sTIC) in hemodialysis patients.
This case-control study was performed in 52 hemodialysis patients and 49 healthy controls.
sTIC was measured by enzymatic assay.
The sTIC was significantly (P< 0.001) lower in hemodialysis patients (1.87 ± 0.67 µmol / min / mL) than healthy controls (2.83 ± 0.44 µmol / min / L).
Reduction of sTIC may be due to the oxidation of methionine residue in the reactive site of alpha-1 antitrypsin.
American Psychological Association (APA)
Hashimi, Muhammad& Mehrabifar, Hamid& Homayooni, Fatimah& Nadiri, Muhammad& Muntazarifar, Farzaneh& Ghavami, Said. 2009. Serum trypsin inhibitory capacity in hemodialysis patients. Saudi Journal of Kidney Diseases and Transplantation،Vol. 20, no. 4, pp.604-607.
https://search.emarefa.net/detail/BIM-37226
Modern Language Association (MLA)
Hashimi, Muhammad…[et al.]. Serum trypsin inhibitory capacity in hemodialysis patients. Saudi Journal of Kidney Diseases and Transplantation Vol. 20, no. 4 (Dec. 2009), pp.604-607.
https://search.emarefa.net/detail/BIM-37226
American Medical Association (AMA)
Hashimi, Muhammad& Mehrabifar, Hamid& Homayooni, Fatimah& Nadiri, Muhammad& Muntazarifar, Farzaneh& Ghavami, Said. Serum trypsin inhibitory capacity in hemodialysis patients. Saudi Journal of Kidney Diseases and Transplantation. 2009. Vol. 20, no. 4, pp.604-607.
https://search.emarefa.net/detail/BIM-37226
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 606-607
Record ID
BIM-37226
