Magnesium sulfate, ketorolac, propofol, ketamine, and xylazine anesthetic protocol in rabbits

Abstract EN

The study aimed to evaluate the combination of Magnesium sulfate (Mg), ketorolac (Kr), Propofol (P), Ketamine (K), and Xylazine(X) anesthetic protocol in anesthesia and analgesia of rabbits.

Twenty healthy male rabbits, weighing (1.300 ± 0.200 kg) were used in the study.

All rabbits were randomly assigned to four groups of five rabbits injected with the different protocols (G1(p10k50mg50), G2(p10k50kr10), G3(p10 k50 kr10mg50), and G4(p10 k50 kr10mg50 x 5)) of anesthesia intravenously in the marginal ear vein.

The heart rate (HR), respiratory rate (RR), rectal temperature (RT) were taken before giving the drugs (Time 0 (control reading)), and then after 5, 10, 15, 20, 30, 45, 60,and 75 minutes of giving anesthesia.

The induction time, duration of anesthesia, degree of analgesia, muscle relaxation and recovery time were recorded also.

The anesthetic protocol in G3 (p10 k50 kr10mg50) is seen suitable for short operations (gives 24.2 minutes of surgical anesthesia), and the anesthetic protocol in G4 (p10 k50 kr10mg50 x 5) is seen suitable for long operations (gives 43.5 minutes of surgical anesthesia), and no signs of pain with the intravenously injection of propofol.