Relation of magnesium level to cyclosporine and metabolic complication in renal transplant recipient
Joint Authors
Lessan Pezeshki, Mahbub
Ahmadi, Farrukh Lagha
Nusayri, Rozita
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 20, Issue 5 (31 Oct. 2009), pp.766-769, 4 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2009-10-31
Country of Publication
Saudi Arabia
No. of Pages
4
Main Subjects
Topics
- Kidneys
- Magnesium
- Metabolic disorders
- Organ transplantation
- Complications(Medicine)
- Immune response
- Immunosuppressive agents
Abstract EN
Cyclosporine is the main immunosuppressive drug used for renal transplant recipients in order to prevent transplant rejection.
Although the drug has increased the survival of patients and grafted organ, it has some side effects independent of its effect on the immune system.
This study was done to evaluate the effect of cyclosporine on serum Mg level and its metabolic side effects in renal allograft patients.
157 (62 female and 95 male) renal transplant recipients treated with cyclosporine to prevent transplant rejection were included in the study.
Clinical and biochemical data along with cyclosporine levels was documented.
Mean serum Mg level was 196 ± 0.31 mg/dL and mean serum cyclosporine level was 371 ± 192 µg/dL.
Hypomagnesemia was detected in 16 (10.2%) with a negative significant correlation with cyclosporine levels, serum creatinine, plasma LDL, fasting Blood sugar and uric acid.
In conclusion according to the results of this study there is a significant correlation between cyclosporine and hypomagnesemia.
Therefore, routine measurement of serum Mg and its treatment seems necessary to prevent its complications.
American Psychological Association (APA)
Ahmadi, Farrukh Lagha& Nusayri, Rozita& Lessan Pezeshki, Mahbub. 2009. Relation of magnesium level to cyclosporine and metabolic complication in renal transplant recipient. Saudi Journal of Kidney Diseases and Transplantation،Vol. 20, no. 5, pp.766-769.
https://search.emarefa.net/detail/BIM-37382
Modern Language Association (MLA)
Ahmadi, Farrukh Lagha…[et al.]. Relation of magnesium level to cyclosporine and metabolic complication in renal transplant recipient. Saudi Journal of Kidney Diseases and Transplantation Vol. 20, no. 5 (Oct. 2009), pp.766-769.
https://search.emarefa.net/detail/BIM-37382
American Medical Association (AMA)
Ahmadi, Farrukh Lagha& Nusayri, Rozita& Lessan Pezeshki, Mahbub. Relation of magnesium level to cyclosporine and metabolic complication in renal transplant recipient. Saudi Journal of Kidney Diseases and Transplantation. 2009. Vol. 20, no. 5, pp.766-769.
https://search.emarefa.net/detail/BIM-37382
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 769.
Record ID
BIM-37382