Evaluation of serum osteocalcin and osteopontin levels as bone biochemical markers in postmenopausal women
Joint Authors
al-Osami, Muhammad H.
Turki, Kisma M.
Muhammad, Nawar Samir
Source
al-Kindy College Medical Journal
Issue
Vol. 9, Issue 2 (31 Dec. 2013), pp.40-44, 5 p.
Publisher
University of Baghdad al-Kindi College of Medicine
Publication Date
2013-12-31
Country of Publication
Iraq
No. of Pages
5
Main Subjects
Topics
Abstract EN
Studies discussing the correlation between biochemical markers of bone turnover and the diagnosis of osteoporosis in postmenopausal Iraqi women are rare.
This study is devoted to find out the significance of serum osteocalcin (OC) and osteopontin (OPN) levels with the incidence of osteoporosis and its major complication (fracture).
Objjecttiives:: to investigate the significance of bone turnover biochemical markers; serum osteocalcin and serum osteopontin in evaluating osteoporosis for postmenopausal Iraqi women with and without history of vertebral fracture, as well as to explore the relationship of these markers with bone mineral density (BMD).
Metthods:: Fifty seven postmenopausal women whose ages are fifty years old and over, categorized into two groups: osteoporosis postmenopausal women (n=30), and healthy postmenopausal women (n=27).
All sera samples were analyzed for serum alkaline phosphatase, calcium and phosphorous by using spectrophotometric kit.
Serum OC and OPN levels were measured by immunoassay (ELISA) kits.
BMD were measured by (DEXA).
Resulltts:: BMD and T-score were significantly lower in osteoporotic postmenopausal group as compared with healthy group (p=0.0001).
Serum OC levels and serum OPN levels were elevated significantly in osteoporotic postmenopausal group as compared with healthy group (p=0.0001).
Concllusiions:: The levels of OC and OPN in serum could be used as a biochemical indicator in the early diagnosis of osteoporosis postmenopausal women.
American Psychological Association (APA)
Turki, Kisma M.& al-Osami, Muhammad H.& Muhammad, Nawar Samir. 2013. Evaluation of serum osteocalcin and osteopontin levels as bone biochemical markers in postmenopausal women. al-Kindy College Medical Journal،Vol. 9, no. 2, pp.40-44.
https://search.emarefa.net/detail/BIM-374213
Modern Language Association (MLA)
Turki, Kisma M.…[et al.]. Evaluation of serum osteocalcin and osteopontin levels as bone biochemical markers in postmenopausal women. al-Kindy College Medical Journal Vol. 9, no. 2 (2013), pp.40-44.
https://search.emarefa.net/detail/BIM-374213
American Medical Association (AMA)
Turki, Kisma M.& al-Osami, Muhammad H.& Muhammad, Nawar Samir. Evaluation of serum osteocalcin and osteopontin levels as bone biochemical markers in postmenopausal women. al-Kindy College Medical Journal. 2013. Vol. 9, no. 2, pp.40-44.
https://search.emarefa.net/detail/BIM-374213
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 43-44
Record ID
BIM-374213