The combination effect of lidocaine, ketamine and atracurium in intravenous regional anesthesia
Joint Authors
Haydar, Hasan Sarhan
al-Mahdi, Fayiz Ahmad
Source
al-Kindy College Medical Journal
Issue
Vol. 9, Issue 2 (31 Dec. 2013), pp.61-63, 3 p.
Publisher
University of Baghdad al-Kindi College of Medicine
Publication Date
2013-12-31
Country of Publication
Iraq
No. of Pages
3
Main Subjects
Topics
Abstract EN
intravenous regional anaesthesia (IVRA) is an effective method of producing anaesthesia of the extremities.
Disadvantages are the rapid loss of anaesthesia after the deflation of the tourniquet and the rapid development of postoperative pain.
It is important to search for agents with longer durations of action, better nerve fibre selectivity, lesser degrees of motor blockade and lower incidences of systemic toxicity.
Objjecttiives:: This study was designed to evaluate and compare the clinical effects of intravenous regional anaesthesia, with lidocaine alone, or in a combination with ketamine and atracurium for better analgesia, and to examine the possible clinical advantages of using muscle relaxants (i.e., atracurium) with intravenous regional anaesthesia.
Metthods:: In prospective, randomized study, sixty patient ASA physical status I, aged 20-50years underwent surgeries on distal regions of upper limbs, patient assigned randomly into 3 groups each of 20 patients, group I received 30ml of 0.5% lidocaine (150mg), group II received 30ml of mixing 0.5% of lidocaine (100mg) plus 30mg ketamine, while group III received 30ml of mixing 0.5% lidocaine (100mg) plus 30mg ketamine plus 2mg atracurium.
All the results were tabulated and analyzed statistically with student's unpaired t-test and chi-square test.
Resulltts:: Addition of 30mg of ketamine to 0.5% lidocaine resulted in rapid onset of sensory block, motor block, and lower visual analogue scale scores for pain compared with the group that received lidocaine only.
The addition of atracurium to the combination of lidocaine and ketamine resulted in improved operating conditions and rapid onset of both sensory and motor blocks with less pain during surgery.
Concllusiions:: drug combination of ketamine, atracurium and low dose of lidocaine lead to rapid onset of sensory block, motor block, lower VAS score for pain, and decrease adverse effect of Bier’s block accompany lidocaine alone, decrease drowsiness which accompany ketamine use alone in IVRA.
American Psychological Association (APA)
Haydar, Hasan Sarhan& al-Mahdi, Fayiz Ahmad. 2013. The combination effect of lidocaine, ketamine and atracurium in intravenous regional anesthesia. al-Kindy College Medical Journal،Vol. 9, no. 2, pp.61-63.
https://search.emarefa.net/detail/BIM-374240
Modern Language Association (MLA)
Haydar, Hasan Sarhan& al-Mahdi, Fayiz Ahmad. The combination effect of lidocaine, ketamine and atracurium in intravenous regional anesthesia. al-Kindy College Medical Journal Vol. 9, no. 2 (2013), pp.61-63.
https://search.emarefa.net/detail/BIM-374240
American Medical Association (AMA)
Haydar, Hasan Sarhan& al-Mahdi, Fayiz Ahmad. The combination effect of lidocaine, ketamine and atracurium in intravenous regional anesthesia. al-Kindy College Medical Journal. 2013. Vol. 9, no. 2, pp.61-63.
https://search.emarefa.net/detail/BIM-374240
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 63
Record ID
BIM-374240