Physiological disturbances in postmenopausal women

Abstract EN

The pathophysiology of menopause is attributed to decreased levels of estrogen hormone.

Estrogen is known to have multiple functions within the body of women and its deficiency after menopause predispose the females to several physiological disturbances.

The present study was designed to investigate changes occurring in postmenopausal women.

Thirteen healthy women involved in this study : 15 pretmenopausal women (24-27 years) and postmenopausal women (55-57 years).

It was found that the levels of follicle stimulating hormone (FSH) pointed out a significant increase (P < 0.01) associated with a significant decrease (P < 0.01) in the levels of estrogen (estradiol) hormone in postmenopausal women in a comparison with premenpausal women.

Levels of super-oxide dismutase activity (SOD), concentration of vitamin-C, and serum copper pointed out a significant decrease (P < 0.05) in postmenopausal women when compared with premenopausal women.

It had been found that the levels of serum blood glucose, serum zinc, and serum calcium showed a significant increase (P < 0.05) in post-menopausal women in a comparison with pre-menopausal women.

Changes summarized above might be attributed to estrogen hormone deficiency in postmenopausal women.