Predicting operability in children with acyanotic congenital heart diseases and severe pulmonary hypertension

Abstract EN

Objective: To investigate whether peri-operative risk stratification of children with ventricular septal defect (VSD) and complete atrioventricular septal defect (CAVSD) complicated with elevated pulmonary vascular resistance could be predicted solely based on measuring systemic oxygen saturation (SaO2) without performing cardiac catheterization.

Methods: Records of patients with VSD and CAVSD, who underwent cardiac catheterization from 2002 to 2012 were reviewed and grouped as low (A) and high (B) risk, based on the pulmonary vascular resistance (PVRI) of 6 or >6 Woods units (WU) in room air, respectively.

Patients in group B underwent oxygen study to assess pulmonary vascular reactivity.

Patients with PVRI 6 6 WU in either room air or on 100% oxygen were deemed operable.

Results: Seventy-six patients; (VSD =45, CAVSD = 31) underwent measurement of pulmonary vascular resistance.

All patients with VSD were operated.

Forty-two of them had systemic oxygen saturation (SaO2)P 94%.

Twenty-four of 31 patients with CAVSD were operated and had SaO2P 83%.

SaO2 of P83% in CAVSD and P94% in VSD had sensitivity and specificity of 95% and 100%, respectively to predict pulmonary vascular resistance based operability.

Conclusion: Oxygen saturation on pulse oximetry of P94% in children with VSD and 83% with CAVSD accurately identified operable patients.

This criterion may be used as an alternate to invasive assessment of pulmonary vascular resistance.

Outcome of operable patients having PVRI> 6 WU in room air is good and similar to those with PVRI <6 WU.