Effect of platelet-rich plasma on nasal mucociliary clearance after submucous diathermy of inferior turbinate

Abstract EN

Objective: To determine the effectiveness of topical application of platelet -rich plasma (PRP) following submucous diathermy (SMD) in promoting the normal ciliary function and improving the healing of nasal turbinate.

Patients and methods: This is a prospective randomized single blinded study done on 60 patients with inferior turbinate hypertrophy (with no or minimal septal deviation).

They were divided into 2 groups, study group A consisting of 30 patients who were candidates for bilateral SMD and then PRP was applied; and control group B (30 patients) who were candidates for the same surgery but saline was used instead of PRP.

Both groups were followed up after 3 days postoperative, then at 1 week, 2 weeks, one month and 2 months consecutively.

Nasal mucociliary clearance (NMC) before surgery was assessed (baseline) and was compared to the NMC in the two-week and twomonth post operative periods.

Results: Nasal mucociliary clearance was improved in both patient groups but it was statistically more significant in group A (with PRP).

Conclusion: Platelet-rich plasma has an effective role after submucous diathermy in improvement of nasal mucociliary clearance and decreased incidence of bleeding and crust formation.