Morphometric analysis of oral submucous fibrosis and its correlation with histological staging and clinical severity of trismus
Joint Authors
Mitra, Bhaskar
Debnath, Sharmistha
Paul, Biswanath
Saha, Tariq Nath
Maity, Asoke
Source
Egyptian Journal of Ear, Nose, Throat and Allied Sciences
Issue
Vol. 14, Issue 2 (31 Jul. 2013), pp.85-90, 6 p.
Publisher
Egyptian Society of Ear Nose Throat and Allied Science
Publication Date
2013-07-31
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Topics
Abstract AR
Aim: To quantify the histopathological changes in oral submucous fibrosis morphometrically and to correlate those findings with the histological grading and clinical severity of trismus.
Methods: A total of hundred histological sections of oral submucous fibrosis were analysed morphometrically by using interactive image analysis system (Image Pro-Plus,V 6.0).
Histological staging and the severity of trismus were then compared with the morphometry results.
ANOVA and Pearson’s chi square tests were applied using the software SPSS V.
13.0 for statistical analysis.
Results: The thickness of the epithelium and subepithelial collagen showed no statistically significant differences between the different stages (p value > 0.05).
However, blood vessel density, mean blood vessel area and mean diameter of the vessels were indirectly proportional to the histological stages (p value <0.001).
Histological stages directly correlate the frequency of trismus, but the severity of trismus showed relation neither with the staging nor with the degree of collagenization, measured morphometrically (p value >0.05).
Abstract EN
Aim : To quantify the histopathological changes in oral submucous fibrosis morphometrically and to correlate those findings with the histological grading and clinical severity of trismus.
Methods : A total of hundred histological sections of oral submucous fibrosis were analysed morphometrically by using interactive image analysis system (Image Pro-Plus,V 6.0).
Histological staging and the severity of trismus were then compared with the morphometry results.
ANOVA and Pearson’s chi square tests were applied using the software SPSS V.
13.0 for statistical analysis.
Results : The thickness of the epithelium and subepithelial collagen showed no statistically significant differences between the different stages (p value > 0.05).
However, blood vessel density, mean blood vessel area and mean diameter of the vessels were indirectly proportional to the histological stages (p value < 0.001).
Histological stages directly correlate the frequency of trismus, but the severity of trismus showed relation neither with the staging nor with the degree of collagenization, measured morphometrically (p value > 0.05).
American Psychological Association (APA)
Debnath, Sharmistha& Mitra, Bhaskar& Paul, Biswanath& Saha, Tariq Nath& Maity, Asoke. 2013. Morphometric analysis of oral submucous fibrosis and its correlation with histological staging and clinical severity of trismus. Egyptian Journal of Ear, Nose, Throat and Allied Sciences،Vol. 14, no. 2, pp.85-90.
https://search.emarefa.net/detail/BIM-375077
Modern Language Association (MLA)
Debnath, Sharmistha…[et al.]. Morphometric analysis of oral submucous fibrosis and its correlation with histological staging and clinical severity of trismus. Egyptian Journal of Ear, Nose, Throat and Allied Sciences Vol. 14, no. 2 (Jul. 2013), pp.85-90.
https://search.emarefa.net/detail/BIM-375077
American Medical Association (AMA)
Debnath, Sharmistha& Mitra, Bhaskar& Paul, Biswanath& Saha, Tariq Nath& Maity, Asoke. Morphometric analysis of oral submucous fibrosis and its correlation with histological staging and clinical severity of trismus. Egyptian Journal of Ear, Nose, Throat and Allied Sciences. 2013. Vol. 14, no. 2, pp.85-90.
https://search.emarefa.net/detail/BIM-375077
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 89-90
Record ID
BIM-375077