Eotaxin, RANTES and tumor necrosis factor alpha levels in allergic rhinitis
Joint Authors
al-Najjar, Muhammad
al-Sharqawi, Asir
al-Mursi, Shawqi
Source
Egyptian Journal of Ear, Nose, Throat and Allied Sciences
Issue
Vol. 12, Issue 1 (31 Mar. 2011), pp.33-37, 5 p.
Publisher
Egyptian Society of Ear Nose Throat and Allied Science
Publication Date
2011-03-31
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Topics
Abstract EN
Objectives: The objectives of this study were to estimate the levels of eotaxin, RANTES and tumor necrosing factor-1 in allergic rhinitis and their relation to disease severity.
Study design: Prospective study.
Setting: Mansoura University Hospital.
Patients and methods: Twenty nine patients suffering from allergic rhinitis were included in this study (19 patients with allergic rhinitis and 10 patients control group).
The patients underwent estimation of eotaxin, RANTES, TNF-1 in the nasal wash using Elisa technique.
The patients were divided according to the disease severity into mild allergic rhinitis, severe allergic rhinitis and control groups.
Results: The mean values of eotaxin, RANTES, TNF-1 in severe allergic rhinitis (33.6 ±11.07 pg/ml, 72.17 ±87.61 pg/ml, 25.47 ± 4.04 pg/ml) were statistically higher than in mild allergic rhinitis (9.80 ± 6.79 pg/ml, 10.50 ±6.90 pg/ml, 12.99± 3.27 pg/ml) and the mean values of all these parameters were higher in both groups compared to control group (0.6 ± 0.69 pg/ml, 0.65 ± 0.74 pg/ml, 0.63 ± 0.54 pg/ml).
Conclusion: This study suggests the role of local chemokines in the pathogenesis of allergic rhinitis as well as their possible relation to the severity of the disease which may direct the attention to therapeutic trials against these locally produced chemokines.
American Psychological Association (APA)
al-Sharqawi, Asir& al-Mursi, Shawqi& al-Najjar, Muhammad. 2011. Eotaxin, RANTES and tumor necrosis factor alpha levels in allergic rhinitis. Egyptian Journal of Ear, Nose, Throat and Allied Sciences،Vol. 12, no. 1, pp.33-37.
https://search.emarefa.net/detail/BIM-375122
Modern Language Association (MLA)
al-Najjar, Muhammad…[et al.]. Eotaxin, RANTES and tumor necrosis factor alpha levels in allergic rhinitis. Egyptian Journal of Ear, Nose, Throat and Allied Sciences Vol. 12, no. 1 (Mar. 2011), pp.33-37.
https://search.emarefa.net/detail/BIM-375122
American Medical Association (AMA)
al-Sharqawi, Asir& al-Mursi, Shawqi& al-Najjar, Muhammad. Eotaxin, RANTES and tumor necrosis factor alpha levels in allergic rhinitis. Egyptian Journal of Ear, Nose, Throat and Allied Sciences. 2011. Vol. 12, no. 1, pp.33-37.
https://search.emarefa.net/detail/BIM-375122
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 36-37
Record ID
BIM-375122