Antibacterial activity of different types of honey in comparison to ciprofloxacin against multidrug- resistance pseudomonas aeruginosa isolated from infected burn

Abstract EN

Despite recent advances in antimicrobial chemotherapy and burns management, infection continues to be an important problem in the burns.

Treatment of multi-drug resistant Pseudomonas aeruginosa, which causes burn infection, is a big challenge in clinics and needs novel strategies.

Failure of the current treatment strategies to control many cases of burns infections, the local and systemic adverse effects that are produced by many topical antibiotics (especially in infants, children, pregnant ladies, and elderly people), and the delay of healing caused by many antiseptics, make a strong motive to find out a new, safe and effective products.

Many recent studies were done to find out natural products that have antimicrobial properties, and enhance the healing process.

This study aimed to investigate the in vitro activity of different types of honey against P.

aeruginosa in comparison to the ciprofloxacin one of the antibiotics used in treatment of burns infection by using disk diffusion method and agar dilution MICs assay.

The mean ± SE inhibition zone in mm were (12.1 ± 0.41, 11.25 ± 0.27, 11.05 ± 0.29) and MICs {(20 %-10 %), 20 %, 20 %} for Sider, Acacia, Eucalyptus respectively.

So the conclusion was that all tested types of honey exerted a good in vitro antimicrobial activity against all tested isolates.