The effect of sever glucose-6-phosphate dehydrogenase (G6PD)‎ deficiency on the activity of white blood cells for a female medical students in Basrah University

Abstract EN

This study involved (57) female medical student, aged between (19-24) years, subdivided into two groups, control group that consist of (30) female with normal level of G6PD enzyme and case group that consist of (27) female with severe G6PD deficiency.

Both groups have hemoglobin type AA, and white blood cells were estimated for them.

We tried in this study to identify the effect of sever G6PD deficiency on the phagocytic activity of non isolated granulocytes from the whole blood, to mirror the in vivo stimulation of granulocytes and the effect of severe G6PD deficiency on their phagocytic activity.

We demonstrate a statistically significant proportion (P < 0.05) between the granulocytes phagocytic activity and severe G6PD deficiency.

This could form the basis for drug development in order to prevent or treat G6PD deficiency-related disease and thus unburden the public health system.