The efficacy of metformin in treatment of ovarian cysts

Abstract EN

This study reflects the effectiveness of metformin (hypoglycemic agent) in medical treatment of ovarian cysts ; compared with hormonal therapies (medroxyprogesteron acetate and \ or conjugated estrogens vaginal cream).

Or treatment by both metformin together with medroxyprogesteron and \ or conjugated estrogen vaginal cream.

And it shows that the use of both drugs (medroxyprogesteron 5mg \ day for 20 days for two courses with interval of 8 days in between, and \ or conjugated estrogen vaginal cream 0.625mg twice daily together with metformin 500mg) was more effective (89.48 %) than the uses of metformin alone (76.47), and medroxyprogesteron and \ or conjugated estrogens vaginal cream (68.75 %), in the treatment of the ovarian cysts.