Role of sildenafil in treatment of pulmonary hypertension in congenital heart diseases for children in Hilla Province

Abstract EN

The study was performed to determine the effect of Sildenafil in treatment of pulmonary hypertension in congenital heart disease for children following (15, 30, 45, 60, 75, 90) day administration of (0.2, 0.4, 0.6, 0.8, 1) mg / kg / dose-6 times daily.

Resulting in a significant decrease (p < 0.05) in Pulmonary Artery pressure and Tricuspid pressure and a significant increase (p < 0.05) in percent of oxygen saturation in the blood and Pulmonary Artery Acceleration Time.

Result of this study says that sildenafil has a great effect in treatment of the secondary type of pulmonary hypertension and has negligible effect on primary pulmonary hypertension.