Comparing effects of interleukin-2 and interleukin-4 on the expression of MHC class II, CD80 and CD86 on polymorphonuclear neutrophils
Author
Abd al-Salam, Baha Qinawi Abd al-Husayn
Source
The Egyptian Journal of Medical Human Genetics
Issue
Vol. 11, Issue 2 (31 Dec. 2010), pp.115-120, 6 p.
Publisher
Egyptian Society of Human Genetics
Publication Date
2010-12-31
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Topics
Abstract EN
Polymorphonuclear neutrophils (PMN) have contributed only to the innate immune response, due to their phagocytosis activity.
They have a short life time.
Some studies of PMN cytokine production and expression of numerous cell surface proteins have suggested that PMN are likely to influence adaptive responses and may satisfy the criteria of antigen presenting cells.
Flow cytometry was used in the present study for the detection of cell surface major histocompatibility complex (MHC) class II, CD80 and CD86 required for antigen presentation and subsequent T-cell activation.
Human peripheral blood neutrophils were used for this purpose.
In vitro stimulation of PMN with IL-2 or IL-4 for 24 h showed expression of MHC class II, CD80 and CD86.
These observations, therefore, provide support to the hypothesis that human PMN have the potential to express molecules required for antigen presentation.
American Psychological Association (APA)
Abd al-Salam, Baha Qinawi Abd al-Husayn. 2010. Comparing effects of interleukin-2 and interleukin-4 on the expression of MHC class II, CD80 and CD86 on polymorphonuclear neutrophils. The Egyptian Journal of Medical Human Genetics،Vol. 11, no. 2, pp.115-120.
https://search.emarefa.net/detail/BIM-380088
Modern Language Association (MLA)
Abd al-Salam, Baha Qinawi Abd al-Husayn. Comparing effects of interleukin-2 and interleukin-4 on the expression of MHC class II, CD80 and CD86 on polymorphonuclear neutrophils. The Egyptian Journal of Medical Human Genetics Vol. 11, no. 2 (2010), pp.115-120.
https://search.emarefa.net/detail/BIM-380088
American Medical Association (AMA)
Abd al-Salam, Baha Qinawi Abd al-Husayn. Comparing effects of interleukin-2 and interleukin-4 on the expression of MHC class II, CD80 and CD86 on polymorphonuclear neutrophils. The Egyptian Journal of Medical Human Genetics. 2010. Vol. 11, no. 2, pp.115-120.
https://search.emarefa.net/detail/BIM-380088
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 120
Record ID
BIM-380088