Neurobrucellosis presenting with hearing loss, gait disturbances and diffuse white matter disease on brain magnetic resonance imaging (MRI)
Joint Authors
Jabbur, Rosette A.
Tabbarah, Zuhayr
Source
Issue
Vol. 59, Issue 2 (30 Jun. 2011), pp.105-108, 4 p.
Publisher
Publication Date
2011-06-30
Country of Publication
Lebanon
No. of Pages
4
Main Subjects
Topics
Abstract EN
Purpose : To report an unusual case of neurobrucellosis.
Methods : A 48-year-old man was admitted to Rafik Hariri University Hospital (RHUH) for progressive gait disturbances, hearing loss, and some episodes of chills without documented fever.
The neurological examination showed gait ataxia, tremor in the legs and mild cognitive decline.
The physical exam was otherwise normal.
Results : Magnetic resonance imaging (MRI) of brain showed diffuse, bilateral, confluent, subcortical, and periventricular white matter disease.
Serum agglutination test (SAT) for Brucella was positive in blood and cerebrospinal fluid (CSF).
The patient was treated with a combination of ceftriaxone for one month, and doxycycline and rifampicin for one year and his condition stabilized.
Literature review was performed.
The possible underlying pathophysiological mechanisms are discussed.
Conclusion : Neurobrucellosis is a very rare complication of human brucellosis, and can present with a variety of central nervous system symptomatology (CNS) and MRI changes suggestive of leukoencephalopathy.
Its diagnosis could be challenging and should always be suspected in patients presenting with CNS manifestations and / or diffuse white matter disease visualized on brain MRI, especially in Brucella endemic areas.
American Psychological Association (APA)
Jabbur, Rosette A.& Tabbarah, Zuhayr. 2011. Neurobrucellosis presenting with hearing loss, gait disturbances and diffuse white matter disease on brain magnetic resonance imaging (MRI). Journal Médical Libanais،Vol. 59, no. 2, pp.105-108.
https://search.emarefa.net/detail/BIM-380211
Modern Language Association (MLA)
Jabbur, Rosette A.& Tabbarah, Zuhayr. Neurobrucellosis presenting with hearing loss, gait disturbances and diffuse white matter disease on brain magnetic resonance imaging (MRI). Journal Médical Libanais Vol. 59, no. 2 (2011), pp.105-108.
https://search.emarefa.net/detail/BIM-380211
American Medical Association (AMA)
Jabbur, Rosette A.& Tabbarah, Zuhayr. Neurobrucellosis presenting with hearing loss, gait disturbances and diffuse white matter disease on brain magnetic resonance imaging (MRI). Journal Médical Libanais. 2011. Vol. 59, no. 2, pp.105-108.
https://search.emarefa.net/detail/BIM-380211
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 107-108
Record ID
BIM-380211