Treatment outcomes of female germ cell tumors : the Egyptian national cancer institute experience
Joint Authors
Sabir, Majdi M.
Munir, Manar
Salim, Salim E.
Darwish, Amirah D.
Abd al-Aziz, al-Shayma A.
Zayn al-Din, Ahmad A.
al-Jamal, Masad M.
Source
Journal of the Egyptian National Cancer Institute
Issue
Vol. 26, Issue 2 (30 Jun. 2014), pp.103-108, 6 p.
Publisher
Cairo University National Cancer Institute
Publication Date
2014-06-30
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Topics
Abstract EN
Introduction : Female germ cell tumors (GCTS) are rare tumors that carry a good prognosis.
Aim : To report the experience of the Egyptian National Cancer Institute (ENCI) in managing female GCTs.
Methods : This retrospective study included 19 females with ovarian GCTs presenting to the ENCI between 2006 and 2010.
Results : The median age was 23 years.
Ovaries were the primary site in all patients.
Dysgerminoma and teratoma were the predominant pathologies followed by mixed GCT in females.
Unilateral ovariectomy or ovarian tumorectomy were the classic surgical procedures with R0 resection being feasible in most cases.
Surveillance was adopted in six patients with stage I disease.
Chemotherapy was administered in 63 % of ovarian GCTs with BEP being the commonest regimen with reasonable tolerability and good response rates.
The median OS and EFS were not reached.
The projected 5-year OS rate was 93.8 %.
Both OS and EFS were better in patients responding to chemotherapy than non-responders (p < 0.002).
Stage of disease did not significantly affect OS or EFS.
American Psychological Association (APA)
Sabir, Majdi M.& Zayn al-Din, Ahmad A.& al-Jamal, Masad M.& Salim, Salim E.& Darwish, Amirah D.& Munir, Manar…[et al.]. 2014. Treatment outcomes of female germ cell tumors : the Egyptian national cancer institute experience. Journal of the Egyptian National Cancer Institute،Vol. 26, no. 2, pp.103-108.
https://search.emarefa.net/detail/BIM-380316
Modern Language Association (MLA)
Munir, Manar…[et al.]. Treatment outcomes of female germ cell tumors : the Egyptian national cancer institute experience. Journal of the Egyptian National Cancer Institute Vol. 26, no. 2 (2014), pp.103-108.
https://search.emarefa.net/detail/BIM-380316
American Medical Association (AMA)
Sabir, Majdi M.& Zayn al-Din, Ahmad A.& al-Jamal, Masad M.& Salim, Salim E.& Darwish, Amirah D.& Munir, Manar…[et al.]. Treatment outcomes of female germ cell tumors : the Egyptian national cancer institute experience. Journal of the Egyptian National Cancer Institute. 2014. Vol. 26, no. 2, pp.103-108.
https://search.emarefa.net/detail/BIM-380316
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 107-108
Record ID
BIM-380316