Estimation of serum leptin in female patients with nodal osteoarthritis

Abstract EN

Background : Nodal osteoarthritis is one of the most common arthropathy worldwide, the etiology is uncertain but many biochemical markers are recognized.

Many studies have shown that leptin might have a role in the pathogenesis of osteoarthritis, but little is known about the relation between serum leptin and nodal osteoarthritis.

Subjects and method : 52 women with nodal osteoarthritis and 40 apparently healthy women as a control were included in the study; serum leptin was measured in all subjects.

Student t-test was applied to find out the significance of difference in the mean v.

Results : There was a significant difference in the mean of serum leptin between patients and control groups.

Conclusion : the results of the current study suggest that leptin might have a role in the pathogenesis of nodal osteoarthritis.