CD-markers as an immunological aspect in patients with visceral leishmaniasis

Abstract EN

Back ground : Visceral leishmaniasis is an endemic protozoan disease in Iraq.

Recovery from this disease confers a solid and permanent immunity.

Immunological assessment of our patients was carried out and the results showed a significant reduction in the percentage of CD3, CD56 and a significant increase in the percentage of CD19 in the peripheral blood lymphocyte of VL in comparison with control group.

Patients and methods : Indirect immunofluorescence technique analysis was performed to detect the percentage of CD3, CD19and CD56 positive lymphocytes.

Results : Our results in the patients groups showed decrease in the percentage of CD3, CD56 and increase in the percentage of CD19.

Follow up of patients after treatment showed a significant increase in the percentage of CD3, CD56, but they were still lower than their normal range.

Conclusion : CD3, CD56, were decreased in VL infection then increased after treatment but it was less than its normal range, while CD19 was increased in VL when compared with control group.