Creatine kinase activity and malondialdehyde in the seminal plasma of normospermic infertile males
Joint Authors
al-Yasin, Hadif Zafir
al-Ani, Ghassan T.
Source
Journal of the Faculty of Medicine Baghdad
Issue
Vol. 51, Issue 3 (30 Sep. 2009), pp.336-340, 5 p.
Publisher
University of Baghdad Faculty of Medicine
Publication Date
2009-09-30
Country of Publication
Iraq
No. of Pages
5
Main Subjects
Topics
Abstract EN
Background : Normospermia might be a major problem to the doctor and the infertile couple because the male seminal sample has an accepted seminal parameters during the routine seminal examination and the female partner will be claimed for the infertility and she will suffered from coasty, painful, time consuming, non indicated investigations and treatments.
Our purpose was to measure sperm creatine phosphokinase (CK) activity, which reflects cytoplasmic retention in immature spermatozoa and malondialdehyde in the seminal plasma which is a marker of oxidative stress in normospermic infertile males' seminal samples.
Patient and methods: Nine infertile men with aberrantly normal standard seminal analysis parameters where included in this study and fifteen fertile men samples where used as control.
The seminal kinase and seminal malondialdehyde were calculated in addition to the standard seminal analysis.
Results : significant higher levels of creatine kinase and malondialdehyde in the normospermic infertile samples (p = 0.0001; p = 0.006 respectively) and also significant positive correlation between the seminal creatine kinase and seminal malondialdehyde (p = 0.001; r = 0.613).
These markers did not correlate with the percentage of mid piece abnormalities in the studied samples.
Conclusion: The seminal plasma creatine kinase and seminal malondialdehyde might be accepted methods to differentiate infertile samples from healthy despite the presence of accepted ranges of standard seminal analysis.
American Psychological Association (APA)
al-Ani, Ghassan T.& al-Yasin, Hadif Zafir. 2009. Creatine kinase activity and malondialdehyde in the seminal plasma of normospermic infertile males. Journal of the Faculty of Medicine Baghdad،Vol. 51, no. 3, pp.336-340.
https://search.emarefa.net/detail/BIM-380504
Modern Language Association (MLA)
al-Ani, Ghassan T.& al-Yasin, Hadif Zafir. Creatine kinase activity and malondialdehyde in the seminal plasma of normospermic infertile males. Journal of the Faculty of Medicine Baghdad Vol. 51, no. 3 (2009), pp.336-340.
https://search.emarefa.net/detail/BIM-380504
American Medical Association (AMA)
al-Ani, Ghassan T.& al-Yasin, Hadif Zafir. Creatine kinase activity and malondialdehyde in the seminal plasma of normospermic infertile males. Journal of the Faculty of Medicine Baghdad. 2009. Vol. 51, no. 3, pp.336-340.
https://search.emarefa.net/detail/BIM-380504
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 339-340
Record ID
BIM-380504