Histopathological evaluation of oral lichen planus
Author
Source
Journal of Baghdad College of Dentistry
Issue
Vol. 24, Issue 2S (31 Mar. 2012), pp.48-54, 7 p.
Publisher
University of Baghdad College of Dentistry
Publication Date
2012-03-31
Country of Publication
Iraq
No. of Pages
7
Main Subjects
Topics
Abstract EN
Background : Oral lichen planus (OLP) is a chronic inflammatory disorder affecting mucosal surfaces , which can cause an important discomfort to the patients.
To highlight the most characteristic histopathological findings of OLP which are useful in making a diagnosis of OLP.
In addition, by studying the association of these finings it was hoped that information about pathogenic mechanism would be obtained.
Material and Methods : In this study a retrospective analyses of 194 cases of OLP being diagnosed at Oral and Maxillofacial Pathology Department, College of Dentistry, were obtained over a period of 26 years, spanning from 1985-2010.
We analyzed the age and sex of the patients, clinical type of lichen planus, site and different histopathological finding, comparing them with each others.
Results : (61 %) of the patients are female and (39 %) are males, with an average age for both sexes (49.75 years).
The most frequent clinical form is reticular, presented in (78 %) of cases, and the most common location is buccal mucosa, presented in (60 %) of the patients.
The mononuclear infiltration beneath and adjacent to the epithelium, parakeratosis and degeneration of the basal layer of the epithelium were consistent features.
Linear regression analysis revealed a positive correlation between basal degeneration and mononuclear infiltration and an inverse correlation between the mononuclear infiltrate and the parakeratosis.
Conclusion : Linear regression analysis of the parameters studied provided partial support for a cell-mediated immune mechanism.
American Psychological Association (APA)
Yas, Layla Sabri. 2012. Histopathological evaluation of oral lichen planus. Journal of Baghdad College of Dentistry،Vol. 24, no. 2S, pp.48-54.
https://search.emarefa.net/detail/BIM-381493
Modern Language Association (MLA)
Yas, Layla Sabri. Histopathological evaluation of oral lichen planus. Journal of Baghdad College of Dentistry Vol. 24, no. 2 (2012), pp.48-54.
https://search.emarefa.net/detail/BIM-381493
American Medical Association (AMA)
Yas, Layla Sabri. Histopathological evaluation of oral lichen planus. Journal of Baghdad College of Dentistry. 2012. Vol. 24, no. 2S, pp.48-54.
https://search.emarefa.net/detail/BIM-381493
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 54
Record ID
BIM-381493