Antibacterial efficiency of chlorhexidine digluconate 0.2 % against oral β-hemolytic streptococci and oral staphylococcus aureus in immunocompromised patients

Abstract EN

Background : The use of antimicrobial agents was advocated for a number of years using different compounds that delivered through mouth rinses to control intra-and extra-oral disease in immunocompromised patients.

The purpose of this research is to find out and to compare between the antibacterial properties of 0.2 % chlorhexidine digluconate (CHX)on oral β-hemolytic streptococci and Staphylococcus aureus isolated from patient with renal failure.

Materials and methods : β- hemolytic streptococci and Staphylococcus aureus were isolated stimulated saliva samples collected from patients receiving steroids therapy.

These bacteria were purified and diagnosed according to morphological characteristic, biochemical and antibiotic sucseptibility tests.

Results : Agar diffusion technique demonstrated that chlorexidine digluconate inhibited the growth of both types of isolates, but the antibacterial effect against Staphyllococcus aureus was less than that against β- hemolytic streptococci.

Conclusion : The use of CHX 0.2 % as a mouth wash to remove those pathogens from the oral cavity to inhibit their infections in immunocompromised patients is highly indicated.