Standard continuous ambulatory peritoneal dialysis therapy provides similar initial T-KT V regardless of the patient’s peritoneal membrane transporter category : single-center experience

Abstract EN

Patients on continuous ambulatory peritoneal dialysis (CAPD) are routinely evaluated using the peritoneal equilibrium test (PET) to determine the best method for achieving target total dialysis clearance (T-Kt / V).

In this study, we tested the hypothesis that standard CAPD prescription would achieve an initial T-Kt / V of more than 1.7 in all the patients regardless of their PET measurements.

This is a retrospective study that included patients who started standard CAPD of four two-liter exchanges per day.

The study included 118 patients ; their mean age was 51.5 years with a standard deviation (SD) of 14.39 years.

There were 83 males (70.3 %) and 35 females (29.7 %).

PET and Kt / V were performed during the first four to six weeks of the study.

The PET classified the patients into four categories : 24 (20.3 %), high transporters ; 65 (55.1 %), high average ; 28 (23.7 %), low average ; and one (0.8 %), low transporter.

Patients were then divided in two groups : Group 1 comprised of the high transporters while Group 2 included all the other patients.

The T-Kt / V of the two groups was similar ; in Group 1, it was 2.57 (± 1.17) and in Group 2 it was 2.50 (± 0.88) (P = 0.77).

The T-Kt / V of patients with no residual renal function was also similar ; in Group 1 and Group 2 it was 1.8 (± 0.29) and 1.97 (± 0.56), respectively (P = 0.45).

All patients in our study who started on standard CAPD treatment had an adequate initial T-Kt / V.

Thus, our data demonstrate that all patients with end-stage renal disease can safely begin standard CAPD without PET, which only needs to be performed if the patient encounters trouble in his / her T-Kt / V or fluid removal.