The use of volumetric chest computed tomography in determination of chronic obstructive pulmonary disease phenotypes
Joint Authors
Nimah, Mustafa
Fadil, Athir A.
Abd al-Razzaq, Shayma A.
Source
Journal of the Faculty of Medicine Baghdad
Issue
Vol. 56, Issue 1 (31 Mar. 2014), pp.20-24, 5 p.
Publisher
University of Baghdad Faculty of Medicine
Publication Date
2014-03-31
Country of Publication
Iraq
No. of Pages
5
Main Subjects
Topics
Abstract EN
Background : Chronic Obstructive Pulmonary Disease (COPD) represents one of the major causes of chronic morbidity where, airflow limitation is caused by a mixture of small airways disease and parenchyma destruction.
Objective : to correlate the clinical characteristics of patients with COPD with imaging classification into phenotypes.
Patients and Methods : Thirty patients with stable COPD were examined by chest CT.
Bronchial wall thickness is evaluated by measuring the wall area percentage by identifying the trunk of the apical bronchus of the right upper lobe, while the extent of emphysema was assessed using the percentage of lung voxels with X-ray attenuation values less than -950 HU {automatically calculated by special software}.
Results : Three phenotypes were found : A phenotype (airway-predominant), 66.6 % of total, E phenotype (emphysema predominant), 20 % of total and M phenotype (mixed), 13.3 % of total.
Conclusions : Using volumetric chest CT in patients with chronic obstructive pulmonary diseases determine three disease patterns.
Airway predominant disease which correlate to patients who have clinical & spirometric pattern of chronic bronchitis rather than emphysema.
Emphysema predominant on CT correlated with patients with clinical findings of lung hyperinflation rather than bronchial inflammation.
Patients with mixed CT findings combined of both previously mentioned types found to be correlated with those with overlapped clinical patterns of both chronic bronchitis & emphysema.
American Psychological Association (APA)
Fadil, Athir A.& Nimah, Mustafa& Abd al-Razzaq, Shayma A.. 2014. The use of volumetric chest computed tomography in determination of chronic obstructive pulmonary disease phenotypes. Journal of the Faculty of Medicine Baghdad،Vol. 56, no. 1, pp.20-24.
https://search.emarefa.net/detail/BIM-384705
Modern Language Association (MLA)
Fadil, Athir A.…[et al.]. The use of volumetric chest computed tomography in determination of chronic obstructive pulmonary disease phenotypes. Journal of the Faculty of Medicine Baghdad Vol. 56, no. 1 (2014), pp.20-24.
https://search.emarefa.net/detail/BIM-384705
American Medical Association (AMA)
Fadil, Athir A.& Nimah, Mustafa& Abd al-Razzaq, Shayma A.. The use of volumetric chest computed tomography in determination of chronic obstructive pulmonary disease phenotypes. Journal of the Faculty of Medicine Baghdad. 2014. Vol. 56, no. 1, pp.20-24.
https://search.emarefa.net/detail/BIM-384705
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 23-24
Record ID
BIM-384705