Spirometric changes in patients with diabetes mellitus

Abstract EN

Objective: Complications of D.M.

affect many organ systems and are responsible for majority of morbidity and mortality associated with this disease.

Pulmonary complications of D.M have been poorly characterized, although some authors had reported normal pulmonary function, others found abnormalities in lung volumes, pulmonary mechanics, and diffusing capacity.

Material and Methods: Fifty patients with Diabetes mellitus (DM) were included in this study that had been conducted at Al-Sader teaching hospital in Al-Najaf, 17 had DM type 1 (9 males and 8 females), and 33 patients had DM type 2( 19 male and 14 female), 20 age and sex matched person were included as a control group (11 were male and 9 female).

Spirometric tests were done for the two groups by flowmeter and computerized Spirometry with six parameters {(Vital capacity (VC ), Forced vital capacity (FVC ), Force expiratory volume in first second (FEV1 ) , Force expiratory volume in first second percent (FEV1% ) , Force expiratory volume in first second to force volume capacity (FEV1/FVC ) ,and Peak expiratory flow rate (FEFR)} .

Results: Spirometric tests were found to be significantly lower in the first (Diabetic )as compared to nondiabetic.Sex and duration of DM were not associated with any of the parameter that were considered, the duration of DM was recorded to affect the Spirometric tests , however these differences were not significant statistically.

Type 1 diabetics had more significant deterioration of Spirometric results as compared to type 2 DM.

Conclusion: Spirometric results were lower in diabetics as compared to nondiabetic, and type 1 had more frequent and severe disturbance in Spirometric tests as compared to type 2, on the other hand, sex and duration had no significant effect on Spirometric tests in both types.