![](/images/graphics-bg.png)
Phosphaturic mesenchymal tumour in the temporal bone : a rare presentation
Joint Authors
Ashish, Gaurav
Mathew, John
Thomas, Nihal
Elanthenral, S.
Kapoor, Nitin
Source
Egyptian Journal of Ear, Nose, Throat and Allied Sciences
Issue
Vol. 15, Issue 2 (30 Jul. 2014), pp.149-153, 5 p.
Publisher
Egyptian Society of Ear Nose Throat and Allied Science
Publication Date
2014-07-30
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Topics
Abstract EN
Background : Tumour-induced osteomalacia (TIO) is a rare clinical entity in which secondary osteomalacia is induced by tumour-related products.
There is impaired reabsorption of phosphorus in the renal tubules and hypophosphatemia as a result of over expression of FGF-23 mRNA.
Treatment of choice is considered to be total or near total resection of the tumour.
Methods and results : A 49-year-old man had experienced systemic bone pain and bilateral limb weakness for several months.
He had refractory hypophosphatemia and marked elevation of serum FGF-23 level.
Magnetic resonance imaging (MRI) of the lumbar spine showed a focal lesion in the left temporal bone which was hyper metabolic on positron emission tomography (PET) scan, leading to a diagnosis of TIO.
He underwent lateral skull-base surgery after thorough evaluation of the tumour.
After the en bloc resection, FGF-23 became gradually undetectable, phosphate reabsorption normalised, and all symptoms were resolved.
Conclusions : We present the clinical features and treatment options for this most unusual manifestation of phosphaturic mesenchymal tumour in the temporal bone.
American Psychological Association (APA)
Ashish, Gaurav& Mathew, John& Thomas, Nihal& Kapoor, Nitin& Elanthenral, S.. 2014. Phosphaturic mesenchymal tumour in the temporal bone : a rare presentation. Egyptian Journal of Ear, Nose, Throat and Allied Sciences،Vol. 15, no. 2, pp.149-153.
https://search.emarefa.net/detail/BIM-385317
Modern Language Association (MLA)
Ashish, Gaurav…[et al.]. Phosphaturic mesenchymal tumour in the temporal bone : a rare presentation. Egyptian Journal of Ear, Nose, Throat and Allied Sciences Vol. 15, no. 2 (Jul. 2014), pp.149-153.
https://search.emarefa.net/detail/BIM-385317
American Medical Association (AMA)
Ashish, Gaurav& Mathew, John& Thomas, Nihal& Kapoor, Nitin& Elanthenral, S.. Phosphaturic mesenchymal tumour in the temporal bone : a rare presentation. Egyptian Journal of Ear, Nose, Throat and Allied Sciences. 2014. Vol. 15, no. 2, pp.149-153.
https://search.emarefa.net/detail/BIM-385317
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 152-153
Record ID
BIM-385317