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Metabolic syndrome, insulin resistance and fatty liver in obese Iranian children
Joint Authors
Karamizadeh, Zahrah
Saki, Forough
Source
Iranian Red Crescent Medical Journal
Issue
Vol. 16, Issue 5 (31 May. 2014), pp.1-6, 6 p.
Publisher
Publication Date
2014-05-31
Country of Publication
United Arab Emirates
No. of Pages
6
Main Subjects
Topics
Abstract EN
Background : Obesity is a global epidemic and its morbidities such as metabolic syndrome, insulin resistance, and fatty liver leads to a spectrum of psycho-social and medical consequences.
Objectives : The objective of this study was to investigate the prevalence of fatty liver in obese Iranian children and its' association with metabolic syndrome and insulin resistance.
Patients and Methods : 102 obese Iranian children, referred to pediatric clinics from March 2011 to March 2012, were enrolled in this cross-sectional study.
All the patients were visited by a pediatric endocrinologist, a pediatric gastroenterologist and an expert radiologist in the evaluation of fatty liver grading.
Results : The grade of fatty liver was higher in older children (P = 0.001).
It was also more in taller and heavier children (P = 0.000).
The more the BMI was, the more the fatty liver grade was (P = 0.002).
Severity of fatty liver according to liver sonography in patient had a positive relationship with waist circumference, hip circumference, serum TG, serum FBS, serum fasting insulin, serum ALT, systolic blood pressure and HOMA index and had a negative correlation with the level of alkaline phosphatase.
Severity of fatty liver also had a close relationship with the presence of acanthosis nigricans and HOMA index.
Conclusions : Prevalence of fatty liver is high in our obese children.
It was associated with criteria of metabolic syndrome and insulin resistance, so visceral fat may participate in the pathogenesis of the metabolic syndrome or merely serve as a marker of increased risk for the metabolic complications of obesity.
American Psychological Association (APA)
Saki, Forough& Karamizadeh, Zahrah. 2014. Metabolic syndrome, insulin resistance and fatty liver in obese Iranian children. Iranian Red Crescent Medical Journal،Vol. 16, no. 5, pp.1-6.
https://search.emarefa.net/detail/BIM-385330
Modern Language Association (MLA)
Saki, Forough& Karamizadeh, Zahrah. Metabolic syndrome, insulin resistance and fatty liver in obese Iranian children. Iranian Red Crescent Medical Journal Vol. 16, no. 5 (May. 2014), pp.1-6.
https://search.emarefa.net/detail/BIM-385330
American Medical Association (AMA)
Saki, Forough& Karamizadeh, Zahrah. Metabolic syndrome, insulin resistance and fatty liver in obese Iranian children. Iranian Red Crescent Medical Journal. 2014. Vol. 16, no. 5, pp.1-6.
https://search.emarefa.net/detail/BIM-385330
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 5-6
Record ID
BIM-385330