Effects of halothane anesthesia on patients with abnormal renal function tests

Abstract EN

Thirty patients (age range 10-70 years), (14) 46.7% males and 16 (53.3%) females, all of them presented with abnormal renal functions were studied in Basrah General Hospital during the period from (March to November 2007), for evaluate safety of halothane anesthesia during routine investigations to elective surgeries under general anaesthesia(the common use of halothane known to cause hepatotoxicity), In addition, drugs like analgesics and antibiotics are, also, heavily used particularly in the postoperative period.

Several of these drugs can compromise renal functions, five milliliters from venous blood were taken before operation and then immediately after the operation, and on the first and third day postoperatively.

Blood was tested for (blood urea nitrogen (BUN), serum creatinine and serum uric acid), using appropriate kits.

Seventeenth (56.7%) had repeated exposure to halothane by underwent previous surgeries, and 13 (43.3%) are newly exposed to halothane.

No significance change had been observed in relation to gender of patients for all parameters.

We conclude that laboratory values immediately after surgical operations and for 3 days later have no trend for a major derangement in patients with renal diseases.