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Synthesis and antimicrobial screening of 1, 3, 4-oxadiazole and clubbed thiophene derivatives
Joint Authors
Desai, N. S.
Dodiya, Amit M.
Rajpara, Kiran M.
Rupala, Yogesh M.
Source
Journal of Saudi Chemical Society
Issue
Vol. 18, Issue 3 (31 Jul. 2014), pp.255-261, 7 p.
Publisher
Publication Date
2014-07-31
Country of Publication
Saudi Arabia
No. of Pages
7
Main Subjects
Abstract EN
In the present study, a novel series of 2-{5-[4-(1-aza-2-(2-thienyl)vinyl)phenyl](1,3,4-oxadiazol- 2-ylthio)}-N-arylacetamides (IV)1–12 were synthesized and tested for their antimicrobial activity.
Newly synthesized compounds were screened for their antibacterial and antifungal activities on Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Staphylococcus pyogenes, Candida albicans, Aspergillus niger and Aspergillus clavatus.
The chemical structures of newly synthesized compounds were elicited by IR, 1H NMR, 13C NMR and mass spectral data.
The synthesized bio-active compounds exhibited excellent to moderate antimicrobial activity.
Compounds (IV)5, (IV)6 and (IV)7 possess excellent antibacterial activity whereas compounds (IV)6, (IV)9 and (IV)11 possess excellent antifungal activity.
American Psychological Association (APA)
Desai, N. S.& Dodiya, Amit M.& Rajpara, Kiran M.& Rupala, Yogesh M.. 2014. Synthesis and antimicrobial screening of 1, 3, 4-oxadiazole and clubbed thiophene derivatives. Journal of Saudi Chemical Society،Vol. 18, no. 3, pp.255-261.
https://search.emarefa.net/detail/BIM-387028
Modern Language Association (MLA)
Desai, N. S.…[et al.]. Synthesis and antimicrobial screening of 1, 3, 4-oxadiazole and clubbed thiophene derivatives. Journal of Saudi Chemical Society Vol. 18, no. 3 (Jul. 2014), pp.255-261.
https://search.emarefa.net/detail/BIM-387028
American Medical Association (AMA)
Desai, N. S.& Dodiya, Amit M.& Rajpara, Kiran M.& Rupala, Yogesh M.. Synthesis and antimicrobial screening of 1, 3, 4-oxadiazole and clubbed thiophene derivatives. Journal of Saudi Chemical Society. 2014. Vol. 18, no. 3, pp.255-261.
https://search.emarefa.net/detail/BIM-387028
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 261
Record ID
BIM-387028