In vivo immunohistochemical investigation of the effect of the topical application of growth hormone on the osseointegration of cpti implant
Joint Authors
Warwar, Abd al-Nasir H.
Ghani, Ban A.
Source
Journal of Baghdad College of Dentistry
Issue
Vol. 26, Issue 2 (30 Jun. 2014), pp.58-63, 6 p.
Publisher
University of Baghdad College of Dentistry
Publication Date
2014-06-30
Country of Publication
Iraq
No. of Pages
6
Main Subjects
Topics
Abstract AR
المقدمة : إن الغرسة هي الطريقة المثلى لتعويض الأسنان المفقودة.
إن الغرس الناجح للمواد المطابقة في داخل الأنسجة الحية مع عدم حدوث رفض لهذه المواد قد أحدث ثورة في الطب عامة و طب الأسنان خاصة وقد لوحظ زيادة في استجابة العظم عند إضافة هرمون النمو حول الغرسة السنية.
إن هرمون النمو ربما يعمل كمحفز للعظم في عملية استبدال الغرسان السنية و كذلك يحفز تكامل التعظم.
الهدف الدراسة التقييم النسيجي و النسيجي المناعي الكيميائي لتأثير الاستخدام الموضعي لهرمون النمو على الاندماج العظمي باستخدام غرسة التيتانيون.
Abstract EN
Background : Dental implants are a suitable option for the replacement of some or all missing teeth.
The successful insertion of a biocompatible material into living tissue with little to no evidence of rejection has revolutionized medicine and dentistry.
An increase in bone response was observed with local administration of growth hormone around dental implants.
Growth hormone may act as a bone stimulant in the placement of endosseous dental implants and enhances osseointegration.
The aim of the study was to evaluate immunohistochemically the effect of the topical application of growth hormone on the osseointegration of cpTi implant.
Materials and Methods : Eighty titanium screw implants were inserted in the tibia of the forty adult rabbits.
Growth hormone was applied on experimental implants.
Immunohistochemical tests were performed on the implants of both control and experimental groups for (3 days1, 2, and 6 weeks) healing intervals.
Results : Titanium implants coated with growth hormone revealed an early bone formation, minerlization and maturation in comparison to control.
Immunohistochemical findings revealed positive expression for VEGF in experimental implant in comparison to control one.
Conclusion : Topical application of growth hormone may act as a bone stimulant in the placement of endosseous dental implants and enhances osseointegration.
American Psychological Association (APA)
Warwar, Abd al-Nasir H.& Ghani, Ban A.. 2014. In vivo immunohistochemical investigation of the effect of the topical application of growth hormone on the osseointegration of cpti implant. Journal of Baghdad College of Dentistry،Vol. 26, no. 2, pp.58-63.
https://search.emarefa.net/detail/BIM-387189
Modern Language Association (MLA)
Warwar, Abd al-Nasir H.& Ghani, Ban A.. In vivo immunohistochemical investigation of the effect of the topical application of growth hormone on the osseointegration of cpti implant. Journal of Baghdad College of Dentistry Vol. 26, no. 2 (Jun. 2014), pp.58-63.
https://search.emarefa.net/detail/BIM-387189
American Medical Association (AMA)
Warwar, Abd al-Nasir H.& Ghani, Ban A.. In vivo immunohistochemical investigation of the effect of the topical application of growth hormone on the osseointegration of cpti implant. Journal of Baghdad College of Dentistry. 2014. Vol. 26, no. 2, pp.58-63.
https://search.emarefa.net/detail/BIM-387189
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 62-63
Record ID
BIM-387189