Effect of vitamin C ,folic acid and iron supplements on oxidative stress in preeclamptic women in Hilla city

Abstract EN

Pre-eclampsia is a disease characterized by elevation of blood pressure and protienurea after the 20th week of gestation.

Some supplements are used during pregnancy like vitamin C, folic acid and iron can effect on oxidative stress matter in preeclamptic women and may act as antioxidant.

The aim is to demonstrate the effect of vitamin C, folic acid and iron supplements on the values of reduced glutathione and malondialdehyde (oxidative stress markers) in preeclamptic, non-anemic pregnant women.

The results showed that vitamin C and folic acid reduce the oxidative stress but iron supplements elevate it.

Also the results revealed that the larger dose and early starting of vitamin C reduced the oxidative stress more than lower dose and late starting of it but there is no significant differences when using different doses and different time of starting of folic acid, while the larger dose and early starting of iron supplements elevate the oxidative stress more than lower dose and late starting of it.

It can be concluded that vitamin C and folic acid are beneficial but there is no need to use iron supplements in non anemic preeclamptic women.