Synthesis, Characterization and biological activity study of some novel tri-metal complexes of 1, 3, 5-tri [5-p-methoxy phenyl-1, 3, 4-thiadiazol-2yl] benzene

Abstract EN

-A new tri metal complexes of 1,3,5 – tri – [5-p-alkoxy phenyl – 1,3,4-thiadiazal- 2yl] benzene (L) formed by the condensation of three moles of metal salt with one mole of (L) which formed by condensation of 1,3,5- benzene tricarboxylic acid[3] with three equivalent of appropriate amino – thiadiazole [2] afforded the corresponding Tri- amide compounds [4], and its CO (II), Ni (II), Cu (II), Zn (II), Pd (II) and Pt (IV) complexes have been synthesized.

Their structures have been elucidated on the basis of analytical, magnetic, electrical conductivity and spectral study as well as elemental analyses.

The results are in agreement with the suggested structures.

The results are in agreement with the suggested structure, all complexes showed octahedral geometries except pd (II) and Pt (II) complexes which were square planar.

The synthesized compound and its metal complexes were tested in vitro for antimicrobial activity.