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Retrospective analysis of the T and B cells flow-cross matches in renal transplantation recipient
Joint Authors
Lakshmi Kiran C.
Kamaraju, Suguna Ratnakar
Kancherla, Ravindranath
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 19, Issue 4 (31 Aug. 2008), pp.571-573, 3 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2008-08-31
Country of Publication
Saudi Arabia
No. of Pages
3
Main Subjects
Topics
Abstract EN
Complement-mediated cytotoxic antibodies in conventional cross match, often result in misappropriation of true positives and borderline positives which are detrimental to allograft survival.
Flow cross matches (FCXM) are sensitive to capture even non complement fixing cytotoxic antibodies.
This retrospective study evaluates the utility of FCXM in effectively predicting acute allograft rejection.
A total of 17 cases were processed for FCXM (T and B cell) of whom seven had no rejection episodes, while the remaining 11 had acute rejection despite negative cross match and panel reacting antibodies being negative (less than 20%).
The sensitivity and specificity of the FCXM outcome demonstrated that positive B-cell FCXM has potential to be a good tool in pre-transplant screening.
The current analysis proposes the possible utility of B-cell positive FCXM as a more sensitive parameter in predicting acute allograft rejection prior to transplantation.
American Psychological Association (APA)
Lakshmi Kiran C.& Kamaraju, Suguna Ratnakar& Kancherla, Ravindranath. 2008. Retrospective analysis of the T and B cells flow-cross matches in renal transplantation recipient. Saudi Journal of Kidney Diseases and Transplantation،Vol. 19, no. 4, pp.571-573.
https://search.emarefa.net/detail/BIM-39160
Modern Language Association (MLA)
Kamaraju, Suguna Ratnakar…[et al.]. Retrospective analysis of the T and B cells flow-cross matches in renal transplantation recipient. Saudi Journal of Kidney Diseases and Transplantation Vol. 19, no. 4 (Dec. 2008), pp.571-573.
https://search.emarefa.net/detail/BIM-39160
American Medical Association (AMA)
Lakshmi Kiran C.& Kamaraju, Suguna Ratnakar& Kancherla, Ravindranath. Retrospective analysis of the T and B cells flow-cross matches in renal transplantation recipient. Saudi Journal of Kidney Diseases and Transplantation. 2008. Vol. 19, no. 4, pp.571-573.
https://search.emarefa.net/detail/BIM-39160
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 573
Record ID
BIM-39160