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Tunneled catheter-antibiotic lock for prevention of dialysis catheter-related infections : a single center experience
Author
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 19, Issue 4 (31 Aug. 2008), pp.593-602, 10 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2008-08-31
Country of Publication
Saudi Arabia
No. of Pages
10
Main Subjects
Topics
Abstract EN
Tunneled cuffed central vein catheters (TCC) are widely used for delivering hemodialysis (HD).
Infection is the principal cause of morbidity and mortality associated with central vein catheters in patients on HD.
The optimal strategy to combat TCC infection is controversial.
This prospective study assesses the efficacy of antibiotic-lock therapy using vancomycin and gentamycin in preventing catheter-related blood stream bacterial infection in patients on HD.
A total of 86 TCC in 69 HD patients were enrolled at the time of catheter insertion for delivering HD.
Patients were randomized into two groups: Group I (36 patients-39 insertions) included TCC with antibiotic-lock therapy and Group II (33 patients-47 insertions) with routine TCC management.
Infection-free catheter survival of both groups was evaluated and compared at the end of the 18-month study period.
A total of 72 TCC infections were detected with an incidence rate of 6.78 infections / 1000 dialysis sessions.
The rate of infection was significantly lower in Group I (4.39 / 1000 dialysis sessions) compared to Group II (11.69 / 1000 dialysis sessions), p< 0.001.
The bacteremia rate, as well as rate of clinical sepsis were also significantly lower in Group I than in Group II (p< 0.001).
There was no statistically significant difference in the rate of access site infection in the two groups (p> 0.05).
Our study suggests that antibiotic-lock therapy using a combination of vancomycin and gentamycin is useful in preventing catheter-related blood stream infection in patients on HD.
American Psychological Association (APA)
al-Huwaysh, Abd Allah K.. 2008. Tunneled catheter-antibiotic lock for prevention of dialysis catheter-related infections : a single center experience. Saudi Journal of Kidney Diseases and Transplantation،Vol. 19, no. 4, pp.593-602.
https://search.emarefa.net/detail/BIM-39267
Modern Language Association (MLA)
al-Huwaysh, Abd Allah K.. Tunneled catheter-antibiotic lock for prevention of dialysis catheter-related infections : a single center experience. Saudi Journal of Kidney Diseases and Transplantation Vol. 19, no. 4 (Dec. 2008), pp.593-602.
https://search.emarefa.net/detail/BIM-39267
American Medical Association (AMA)
al-Huwaysh, Abd Allah K.. Tunneled catheter-antibiotic lock for prevention of dialysis catheter-related infections : a single center experience. Saudi Journal of Kidney Diseases and Transplantation. 2008. Vol. 19, no. 4, pp.593-602.
https://search.emarefa.net/detail/BIM-39267
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 600-602
Record ID
BIM-39267